Acute overdosage is unlikely to cause problems. The only harmful effect that follows inhalation of large amounts of the drug over a short time period is suppression of HPA function. Specific emergency action need not be taken. Treatment with Arite Beclometasone 100mcg/actuation Metered Dose Inhaler should be continued at the recommended dose to control the asthma, HPA function recovers in a day or two. If excessive doses of beclometasone dipropionate were taken over a prolonged period a degree of atrophy of the adrenal cortex could occur in addition to HPA suppression. In this event the patient should be treated as steroid dependent and transferred to a suitable maintenance dose of a systemic steroid such as prednisolone. Once the condition is stabilised, the patient should be returned to Arite Beclometasone 50mcg/actuation and 100mcg/actuation Metered Dose Inhaler by the method described.
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